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Medications

Hyaluronidase, Recombinant; Immune Globulin injection

What is this medicine?

IMMUNE GLOBULIN (im MUNE GLOB yoo lin) helps to prevent or reduce the severity of certain infections in patients who are at risk. This medicine is collected from the pooled blood of many donors. It is used to treat immune system problems.

HYALURONIDASE (hye al ur ON i dase) is a natural protein. It is used to improve the effects of other injectable medicines given with this medicine.

How should I use this medicine?

This medicine is for infusion under the skin. It is usually given by a health care professional in a hospital or clinic setting.

If you get this medicine at home, you will be taught how to give this medicine. Use exactly as directed. Take your medicine at regular intervals. Do not take your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • fever

  • headache

  • nausea

  • rash

  • signs and symptoms of a blood clot such as breathing problems; changes in vision; chest pain; severe, sudden headache; pain, swelling, warmth in the leg; trouble speaking; sudden numbness or weakness of the face, arm, or leg

  • signs and symptoms of kidney injury like trouble passing urine or change in the amount of urine

  • stiff neck and sensitivity to light

  • vomiting

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • pain, redness, or irritation at site where injected

  • weak or tired

What may interact with this medicine?

This medicine may interact with the following medications:

  • live virus vaccines, like measles, mumps, or rubella

What if I miss a dose?

It is important not to miss your dose. Call your doctor or health care professional if you are unable to keep an appointment. If you give yourself the medicine and you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Where should I keep my medicine?

Keep out of the reach of children.

If you are using this medicine at home, you will be instructed on how to store this medicine. Throw away any unused medicine after the expiration date on the label.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • diabetes

  • heart disease

  • history of blood clots

  • infection in the area where injection is planned

  • immune system problems

  • kidney disease

  • low levels of immunoglobulin A in the body

  • an unusual or allergic reaction to human immune globulin, hyaluronidase, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Your condition will be monitored carefully while you are receiving this medicine. You may need blood work done while you are taking this medicine.

This medicine contains albumin from human blood. It may be possible to pass an infection in this medicine, but no cases have been reported. Talk to your doctor about the risks and benefits of this medicine.

Check with your doctor or healthcare professional if you get an attack of severe diarrhea, nausea and vomiting, or if you sweat a lot. The loss of too much body fluid can make it dangerous for you to take this medicine.

This medicine can decrease the response to a vaccine. If you need to get vaccinated, tell your healthcare professional if you have received this medicine within the last 8 months. Extra booster doses may be needed. Talk to your doctor to see if a different vaccination schedule is needed.


NOTE:This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider. Copyright© 2018 Elsevier